
March 8 (Reuters) - Johnson & Johnson's   prostate cancer drug Zytiga improved survival in patients who  had not received chemotherapy in a late-stage study, the company  said on Thursday.                
An independent data monitoring committee unanimously  recommended that patients receiving a placebo in the trial be  offered treatment with Zytiga, the company said.                
"This news is clearly a significant positive for J&J. An  approval in the pre-chemo population should more than double the  market opportunity for Zytiga. We would expect physicians to  increase their use of Zytiga off-label in this population once  the data is released, even before official FDA approval is  achieved," Bernstein Research analyst Derrick Sung wrote in a  research note.                
"We continue to believe that 2012 will be a seminal year for  J&J's pharmaceutical franchise, as they will see four of their  recently launched products (Zytiga, Xarelto, Incivo and Stelara)  begin to build sales toward blockbuster status this year," he  added.                
The news sent shares of J&J up 1 percent and shares of  Medivation Inc, which is also developing a prostate  cancer pill that works by targeting the same hormone that Zytiga  targets, up almost 15 percent.                
However, shares of Dendreon Corp fell about 16  percent. Dendreon makes a prostate cancer vaccine, Provenge,  that has a different mechanism of action.                
(Reporting by Kavyanjali Kaushik and Esha Dey in Bangalore; Editing by Gopakumar Warrier and Mark Porter)
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